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http://hdl.handle.net/10077/10292| Title: | Metabolic bone disorders: from bench to bedside | Authors: | Nicolin, Vanessa De Iaco, Doriano Valentini, Roberto |
Keywords: | TRANS2CARE; bone; disorder; osteoclast; co-culture; RANKL | Issue Date: | 2014 | Publisher: | EUT Edizioni Università di Trieste | Source: | Vanessa Nicolin, Doriano De Iaco, Roberto Valentini, Metabolic bone disorders: from bench to bedside, in S. Passamonti, S. Gustincich, T. Lah Turnšek, B. Peterlin, R. Pišot, P. Storici (Eds.), Cross-border Italy-Slovenia biomedical research: are we ready for horizon 2020? Conference proceedings with an analysis of innovation management and knowledge transfer potential for a smart specialization strategy. Trieste, EUT Edizioni Università di Trieste, 2014, pp. 233-236 | Abstract: | Bone is a complex tissue that have many function, when bone remodeling becomes perturbed we can assist at many pathologies. The key factor in these pathologies is a perturbation of RANKL/RANK/OPG pathways. We have tune up a 3D culture system that have the advantage to produce osteoclast cells more physiological than the administration of the recombinant RANKL protein. This can be useful when study new drugs to avoid the cross-reaction with the exogenous cytokines. |
Type: | Book Chapter | URI: | http://hdl.handle.net/10077/10292 | ISBN: | 978-88-8303-572-2 | eISBN: | 978-88-8303-573-9 |
| Appears in Collections: | Trans2Care, 2014. Cross-Border Italy-Slovenia Biomedical Research. Are we ready for Horizon 2020? |
Files in This Item:
| File | Description | Size | Format | |
|---|---|---|---|---|
| Vanessa Nicolin.pdf | 184.02 kB | Adobe PDF |  View/Open |
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