Please use this identifier to cite or link to this item:
http://hdl.handle.net/10077/10302
Title: | X-ray diffraction @ elettra synchrotron: atomic insight of your biomedical target | Authors: | Bais, Giorgio et al. |
Keywords: | X-Ray diffraction; Macromolecular Crystallography; Alzheimer’s disease; CK2 kinase; drug polymorphism; XRD1; Structure Based Drug Design; Active Pharmaceutical Ingredients | Issue Date: | 2014 | Publisher: | EUT Edizioni Università di Trieste | Source: | Giorgio Bais, Alberto Cassetta, Sonia Covaceuszach, Nicola Demitri, Doriano Lamba, Alessandro Pesaresi, Maurizio Polentarutti, X-ray diffraction @ elettra synchrotron: atomic insight of your biomedical target, in S. Passamonti, S. Gustincich, T. Lah Turnšek, B. Peterlin, R. Pišot, P. Storici (Eds.), Cross-border Italy-Slovenia biomedical research: are we ready for horizon 2020? Conference proceedings with an analysis of innovation management and knowledge transfer potential for a smart specialization strategy. Trieste, EUT Edizioni Università di Trieste, 2014, pp. 281-287 | Abstract: | Crystallography is an invaluable tool to understand atomic structure. The knowledge at atomic scale of small and large molecules is crucial for many biomedical and biotechnological applications, ranging from drug design and optimization to enzyme functional studies and engineering. The physical properties of the solid state seen in crystals and powders of both drugs and pharmaceutical excipients are of interest because the nature of the crystalline form of a drug substance, due to polymorphism, may affect both the production and formulation as well as its stability in the solid state, its solution properties and its absorption. We offer a comprehensive access to state of the art X-ray diffraction tools and methodologies, supporting all the steps, from sample preparation to 3D structure analysis. |
Type: | Book Chapter | URI: | http://hdl.handle.net/10077/10302 | ISBN: | 978-88-8303-572-2 | eISBN: | 978-88-8303-573-9 |
Appears in Collections: | Trans2Care, 2014. Cross-Border Italy-Slovenia Biomedical Research. Are we ready for Horizon 2020? |
Files in This Item:
File | Description | Size | Format | |
---|---|---|---|---|
Giorgio Bais.pdf | 545.49 kB | Adobe PDF | ![]() View/Open |
CORE Recommender
Page view(s) 20
907
checked on Jan 27, 2023
Download(s) 20
1,501
checked on Jan 27, 2023
Google ScholarTM
Check
Altmetric
This item is licensed under a Creative Commons License