Please use this identifier to cite or link to this item: http://hdl.handle.net/10077/10302
Title: X-ray diffraction @ elettra synchrotron: atomic insight of your biomedical target
Authors: Bais, Giorgio
et al.
Keywords: X-Ray diffractionMacromolecular CrystallographyAlzheimer’s diseaseCK2 kinasedrug polymorphismXRD1Structure Based Drug DesignActive Pharmaceutical Ingredients
Issue Date: 2014
Publisher: EUT Edizioni Università di Trieste
Source: Giorgio Bais, Alberto Cassetta, Sonia Covaceuszach, Nicola Demitri, Doriano Lamba, Alessandro Pesaresi, Maurizio Polentarutti, X-ray diffraction @ elettra synchrotron: atomic insight of your biomedical target, in S. Passamonti, S. Gustincich, T. Lah Turnšek, B. Peterlin, R. Pišot, P. Storici (Eds.), Cross-border Italy-Slovenia biomedical research: are we ready for horizon 2020? Conference proceedings with an analysis of innovation management and knowledge transfer potential for a smart specialization strategy. Trieste, EUT Edizioni Università di Trieste, 2014, pp. 281-287
Abstract: Crystallography is an invaluable tool to understand atomic structure. The knowledge at atomic scale of small and large molecules is crucial for many biomedical and biotechnological applications, ranging from drug design and optimization to enzyme functional studies and engineering. The physical properties of the solid state seen in crystals and powders of both drugs and pharmaceutical excipients are of interest because the nature of the crystalline form of a drug substance, due to polymorphism, may affect both the production and formulation as well as its stability in the solid state, its solution properties and its absorption. We offer a comprehensive access to state of the art X-ray diffraction tools and methodologies, supporting all the steps, from sample preparation to 3D structure analysis.
URI: http://hdl.handle.net/10077/10302
ISBN: 978-88-8303-572-2
eISBN: 978-88-8303-573-9
Appears in Collections:Trans2Care, 2014. Cross-Border Italy-Slovenia Biomedical Research. Are we ready for Horizon 2020?

Files in This Item:
File Description SizeFormat
Giorgio Bais.pdf545.49 kBAdobe PDFThumbnail
View/Open
Show full item record


CORE Recommender

Page view(s)

748
checked on Apr 11, 2019

Download(s)

1,177
checked on Apr 11, 2019

Google ScholarTM

Check

Altmetric


This item is licensed under a Creative Commons License Creative Commons